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Phospho Biomedical Animation
Приєднався 2 лют 2015
The cells of our bodies hold their own vibrant world, in which all kinds of weird and wonderful things happen. Laboratory research gives us an idea of what that world looks like, providing information on the different components of the cell and the roles they play. Even though this research is contributing to a grand story, we tend to present data as separate snippets, focusing on small parts in great detail.
At Phospho, we put that grand story together. We take structural biology, biochemistry and cell biology data and show how they interlink. Science is an inherently visual pursuit. Using biomedical animations to show how things work will allow you to tell your story to a wider audience without having to dilute the scientific content.
At Phospho, we put that grand story together. We take structural biology, biochemistry and cell biology data and show how they interlink. Science is an inherently visual pursuit. Using biomedical animations to show how things work will allow you to tell your story to a wider audience without having to dilute the scientific content.
Відео
Introducing PromethION 2
Переглядів 3262 роки тому
Oxford Nanopore Technologies are changing the way you sequence.. again. Find out more at: nanoporetech.com/products/promethion-2
Making of: Creating the coronavirus
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A look behind the scenes of our award-winning Lifecycle of SARS-CoV-2 animation.
The lifecycle of SARS-CoV-2
Переглядів 48 тис.2 роки тому
What happens to the cells in our airways during a coronavirus infection? In this animation for Maastricht University we follow the full SARS-CoV-2 replication cycle, going from initial infection all the way through to new virus particles being released from the cell. Chapters: 00:00 Healthy respiratory cells 00:25 Components of the virus 01:06 Variants 01:31 Entering the host cell 02:15 Making ...
Harnessing the immune system against cancer
Переглядів 6752 роки тому
There are two types of T-cells that operate within our immune systems: these are the effector T-cells (cancer killers) and regulatory T-cells (cancer enablers). We made this video for Cancer Research UK to describe exciting new research on an antibody (CD25nib) that signals drugs to kill regulatory T-cells, whilst ignoring effector T-cells. This pioneering approach essentially harnesses the imm...
Adaptive sampling to accelerate DNA sequencing
Переглядів 3262 роки тому
In this video, we explain how Oxford Nanopore's "read until" technology speeds up sequencing experiments with adaptive sampling and helps you focus on regions of interest. Find out more: nanoporetech.com/resource-centre/read-until-adaptive-sampling
Bacterial DNA motors
Переглядів 1,1 тис.2 роки тому
FtsK is a hexameric protein important in chromosome segregation and bacterial cell division. Research by the Loewe laboratory at the MRC LMB has shown how the structural behaviour of Ftsk helps its DNA motor function. Research paper - ncbi.nlm.nih.gov/pmc/articles/PMC7321959/
Protecting tumour-associated macrophages
Переглядів 1,7 тис.2 роки тому
A tumour is a complex micro-environment with a complicated immune system to defend against attacks. One of these defence mechanisms is to create an acidic microenvironment, which shuts down tumour-associated macrophages (TAMs). In this video, we explain the concepts behind Pathios Therapeutics' immune driven cancer therapy that utilises small molecules to restore the tumour attacking capabiliti...
Measuring protein-protein interactions in tissue samples with QFPro
Переглядів 1832 роки тому
In this video, we explain how the FASTBASE QFPro platform works to unveil post-translational modifications and protein-protein interactions in tissue samples. For more information, check out: fastbasesolutions.com/
Building protein filaments
Переглядів 6522 роки тому
Human islet amyloid polpeptide (hIAPP) functions as part of the endocrine system and has key metabolic functions. It can self-aggregate to form amyloid fibrils and these fibrils have clinical significance in diseases such as early onset type-2 diabetes. In this video we show the research done at the Astbury Centre by the Ranson Lab into hIAPP, it's form, function, and clinical relevance. For mo...
Beyond small molecules: Rethinking protein inhibition
Переглядів 9342 роки тому
Scientists at the Astbury Centre are developing new ways of trapping proteins in non-signalling shapes to block protein-protein interactions. In this video, we explain how proteins interact and some of the new ways protein activity can be blocked. Find out more: astbury.leeds.ac.uk/research/research-themes/the-dynamic-interactome/
What are protein hydrogels?
Переглядів 8832 роки тому
Protein hydrogels are networks that are usually formed of folded proteins. Researchers at the Astbury Centre and ISIS have been discovering what happens to these structures when the proteins forming these structures are allowed to unfold. In this video, we go into more detail into the biomechanics of protein hydrogels. Find out more about this research: pubs.acs.org/doi/10.1021/acsnano.1c00353
From membrane proteins to antibiotics
Переглядів 6722 роки тому
β-barrel assembly machinery (BAM) are trans membrane proteins that insert proteins into a cell through changes in their structure. In this video we explain research conducted at the Astbury Centre into the dynamics of BAM and how its structure might be manipulated to create new antibiotics. For more information, see: www.nature.com/articles/s41467-021-24432-x
Genetic modifiers: natural protection against genetic disease
Переглядів 1,5 тис.2 роки тому
Genetic mutations can cause devastating diseases, but not everyone with a particular mutation will get the disease. This is because of a natural form of protection provided by other genes: genetic modifiers. In this video, we'll explain what genetic modifiers are, and showcase Scenic Biotech's revolutionary method to quantify genetic modifiers, opening new avenues for drug discovery. To find ou...
Limited proteolysis and drug development
Переглядів 1,1 тис.2 роки тому
Learn about how Biognosys' Limited Proteolysis (LiP) technology is advancing techniques in mass spectrometry, proteomics, and drug development. For more information, see biognosys.com
Long read sequencing: repetitive regions
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Long read sequencing: repetitive regions
Long read sequencing: what can you do with it?
Переглядів 2,2 тис.3 роки тому
Long read sequencing: what can you do with it?
Handheld DNA sequencing with nanopores
Переглядів 1,4 тис.5 років тому
Handheld DNA sequencing with nanopores
How new protein superglue helps pioneer vaccines - SpyBiotech
Переглядів 2,1 тис.5 років тому
How new protein superglue helps pioneer vaccines - SpyBiotech
The microbiome: gut bacteria & cancer treatment
Переглядів 8606 років тому
The microbiome: gut bacteria & cancer treatment
Phospho Biomedical Animation Showreel 2018
Переглядів 2,9 тис.6 років тому
Phospho Biomedical Animation Showreel 2018
Good morning sir, which animation software have you used. Please guide us too as it looks amazing.
how can i get blood cancer ? any tip ?
My mom has she died
Any news on this
omg i know nothing
2 weeks ago i noticed a lump on my chest wall. It was initially soft. But now it feels a little hard. Its painful every morning when i wake up.
My mom friend son who is 13 years old has blood cancer please pray for him😢
There will probably never be a cure nor a treatment that actually works for it. They earn a colossal amount of money on the current cancer "treatments" they give, and all the doctors have been bought by the pharma companies that sell them. We'll never make.
This video contains an error, but it's an educational one. The animation of spike cleavage would better fit the original SARS than SARS-CoV-2. In the original SARS, both the first cut (S1/S2) and the second cut (S2') happen at the surface of the target cell about to be infected, e.g. both might be done by the cell-surface protein TMPRSS2. But for SARS-CoV-2, the S1/S2 cut was already done well ahead of time, by the soluble protein furin in the Golgi apparatus of the cell where the virus was made. By the time the virus got out of the origin cell and towards the target cell, its S1 and S2 were already cleaved and already only loosely non-covalently bonded. Reference: Jackson et al., 2022 (doi:10.1038/s41580-021-00418-x).
Proteolytic enzymes eat tumors, cysts, and all growths on and in the body. Look into Dr. Nicholas Gonzalez’s work. Antiparasitic meds can help get rid of cancer too because cancer is due to toxicity and parasites, fungus, and bacteria always are present when there is an abundance toxins in the body. Improve bile flow to help your liver detox and you may start seeing parasites and their eggs in the toilet. The more toxins you have, the more parasites you have. These janitors create an anaerobic environment which could suffocate the tissue leading to more necrotic tissue for them to feast on. 🙏 Allopathic doctors aren’t trained in nutrition or on how to support the organs and glands. They don’t blame dis-ease on toxicity because it’s not part of their training. Cancer is big business, unfortunately!
Nestor Falls
None of the proteins are labelled. For instance where is the Furin Protease???
The separately uploaded "scientific version," on Maastrich University's channel, does name the proteins. However, both contain an error regarding furin cleavage. There's a difference between spike protein cleavage in SARS vs. SARS-CoV-2 (Jackson et al., 2022, doi:10.1038/s41580-021-00418-x). This video better fits SARS. In the original SARS, both the first S1/S2 cut and the second S2' cut happen at the surface of the cell about to be infected. But in SARS-CoV-2, furin already cleaved S1/S2 well ahead of time, in the Golgi apparatus of the cell where the virus was made (and furin unlike TMPRSS2 is a soluble protein not a membrane protein). By the time the virus gets out of the origin cell and approaches the target cell, its S1 and S2 have already been cleaved and are only loosely non-covalently bonded.
Kutch Greens
981 Price Creek
In my school aradhya tiwari😢😢😢😢died from blood cancer😢😢😢😢😢😢😢😢
Following where to go could be a clue closer to cureing cancer ❤❤❤god loves you 🎗🎗🎗🎗🎗🎗🎗
Treutel Crest
😢
Had Leukemia 30 years ago! Have been free from it for 25 years!
How
Mattie Curve
Esther Land
Mariana Brook
Archibald Street
789 Guy Drive
Beautiful explanation
My grandpa had this and spread to his brain and he didn’t even remember me
My best friend has blood cancer 😢
To my greatest surprise, I was able to cure the in cancer tumor in my breast without undergoing surgery. All thanks to #DrOria on UA-cam for helping me.
That’s so cool 🎉
Forced adoption research
That so many ways to cure canser i cant decide where to start and chose the one ,actually i havent face a doctor ang complaining my condition as of now i only feel they said symtoms of it
Just lost my ex lover to cancer on Tuesday i have been so interested to learn more about it. Im gonna miss him dearly I can’t stop thinking about him ❤
May their memory be eternal. 🙏🤍☦️ May God grant you peace and strength.
Wonderful animations
My love, my boyfriend has blood cancer. Please pray for him..
Cancer is intercellular microparasites and is cured with antiparasitic drugs
எனக்கு புற்றுநோய் வரட்டும் 🙏
idk why or how but this video felt so comfortable, thank you 💕
beautifully put.
Wow wow wow! A great job!
Hi, thank you for your video. The animation is lit ! I was wondering, if the dmv is made from the host cell membrane, does that mean the vesicle ends up outside the cell? Then, when the subgenomic RNA exits the dmv thought it's pore, it needs to re-enter the cell thought another pore too?
I have been diagnosed with lung cancer. It sucks😢
Cancer is intercellular microparasites and is cured with antiparasitic drugs
How are you now
🙏🏾🙏🏾
@@Ladysugarshaft is he dead?
De cind se lupta ăștia sa cerceteze m am plictisit eu .
Metastasis. 😮
That means US Foreign Policy !
bloody vessels!
My mom got cancer
Cancer is intercellular microparasites and is cured with antiparasitic drugs
How's she now?
@@youpedia4614 shes Good now but she have no hair
Murav'i @
Duru ne gani😅
Assmsunga😅
Naks a ne ajs😅 vegan😅
BUT YOU SEEMS TO BE PRAISING THE CORONA VIROUS PLAYING BEAUTIFUL BACKGROUND MUSIC. YOU ARE MINDLESS ROBOT.
I hope my friend 🧡 gets better 😢